Developing tests to predict long-term organ damage from radiation exposure
Official title: Advanced development of multi-omics based assays to predict late radiation organinjuries - the DEARE-Watch project
Funded at Georgetown University · NIH-11100103 · Data updated 2026-11-12
This study is working on new tests to help people who have been exposed to radiation by checking for the risk of lung and kidney damage later on, using simple samples from their bodies to catch any problems early and improve their health.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgetown University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project start | May 19, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $570,849 |
| NIH project number | 1U01AI189442-01 |
| Project ID | NIH-11100103 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced acute radiation exposure, particularly those affected by radiological accidents or atomic bomb survivors.
✕Less likely to help
Patients who have not been exposed to radiation or those with pre-existing severe organ damage unrelated to radiation may not benefit from this research.
What this research studies
This research focuses on creating advanced tests that can identify the risk of late organ injuries, such as lung and kidney damage, in individuals who have been exposed to radiation. By analyzing biological samples, the project aims to develop predictive algorithms that can assess the likelihood of these injuries occurring months or years after exposure. The approach involves using minimally invasive biomarkers to enable early monitoring and intervention, potentially improving patient outcomes. The research builds on previous findings from animal models and aims to translate these insights into practical applications for human patients.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring and treatment options for individuals at risk of developing serious health issues after radiation exposure.
How similar studies have gone: Previous research has shown promise in using multi-omics approaches to predict radiation injuries, indicating that this methodology has potential for success.
Where this research is happening
-
Georgetown University
Washington, United States Active
Researchers
- Principal investigator: Cheema, Amrita Kaur — Georgetown University
- Study coordinator: Cheema, Amrita Kaur
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.