Multi-omics tools to predict late radiation organ injuries (DEARE-Watch)
Official title: Advanced development of multi-omics based assays to predict late radiation organinjuries - the DEARE-Watch project
Funded at Georgetown University · NIH-11576194 · Data updated 2026-11-12
Aims to create blood and urine tests that use multiple omics signals to forecast long-term damage to lungs and kidneys after acute radiation exposure, helping patients get early care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgetown University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project start | May 19, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $165,000 |
| NIH project number | 3U01AI189442-02S1 |
| Project ID | NIH-11576194 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults or adolescents who are at risk of or have experienced acute radiation exposure and are being monitored for late organ effects.
✕Less likely to help
Patients without exposure to radiation or without risk of delayed organ injury may not benefit.
What this research studies
If you have or could face acute radiation exposure, this project builds advanced tests using blood and urine biomarkers to predict later organ damage. It uses prior findings of omics panels that signal lung and kidney injury months after exposure, with the goal of guiding timely monitoring and treatment. The approach blends minimally invasive sampling with cutting-edge data analysis to identify quienes are at higher risk and when to intervene. The work is led by Georgetown University researchers and seeks to translate lab discoveries into practical tools for emergency care and follow-up.
Why it matters
Potential benefit: If successful, these predictive tests could enable earlier monitoring and intervention to reduce long-term organ damage after radiation exposure.
How similar studies have gone: Previous rodent and human cohort research supports the idea that early omics signals can predict later organ injury, though translation to routine care is ongoing.
Where this research is happening
-
Georgetown University
Washington, United States Active
Researchers
- Principal investigator: Cheema, Amrita Kaur — Georgetown University
- Study coordinator: Cheema, Amrita Kaur
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.