Developing new treatments for human cytomegalovirus infections
Optimization of novel inhibitors of human cytomegalovirus
['FUNDING_OTHER'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11125021
This study is working on new ways to stop the human cytomegalovirus (CMV), which can be really dangerous for people with weakened immune systems, like newborns and organ transplant patients, so they can have safer and better treatment options.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11125021 on ClinicalTrials.gov |
What this research studies
This research focuses on creating novel inhibitors to combat human cytomegalovirus (CMV), a virus that poses significant risks to immunocompromised individuals, including newborns and organ transplant recipients. The approach involves targeting various stages of the viral life cycle to prevent the virus from spreading and causing severe health issues. By developing new therapeutic strategies, the research aims to address the limitations of existing treatments, which often lead to drug resistance and serious side effects. Patients may benefit from safer and more effective options for managing CMV infections.
Who could benefit from this research
Good fit: Ideal candidates for this research include immunocompromised individuals, such as newborns, organ transplant recipients, and patients with AIDS.
Not a fit: Patients who are not immunocompromised or do not have a history of CMV infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatments for patients suffering from CMV-related diseases.
How similar studies have performed: Previous research has shown promise in developing novel antiviral therapies, indicating potential for success in this area.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TORTORELLA, DOMENICO — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: TORTORELLA, DOMENICO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome, Acquired Immunodeficiency Syndrome, Atherosclerotic Cardiovascular Disease, Autoimmune Diseases