Developing new treatments for endometrial cancer using small molecules
Targeting Endometrial Cancer with Novel Small Molecule Modulators of PP2A
This study is looking for new ways to help treat endometrial cancer by finding small molecules that can target a specific protein involved in the disease, which could lead to better treatment options for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-10953932 on NIH RePORTER |
What this research studies
This research focuses on identifying and developing small molecule modulators that target a specific protein, PP2A, which plays a crucial role in the progression of endometrial cancer. By utilizing advanced technologies such as single-cell analysis and organoid manipulation, the research aims to enhance the understanding of how these molecules can effectively inhibit cancer growth. Patients may benefit from innovative treatment options that arise from this work, potentially leading to more effective therapies for endometrial cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with endometrial cancer who are seeking new treatment options.
Not a fit: Patients with other types of cancer or those not diagnosed with endometrial cancer may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new and more effective treatment options for patients with endometrial cancer.
How similar studies have performed: Other research has shown promise in targeting similar molecular pathways in cancer treatment, indicating potential for success in this approach.
Where this research is happening
Omaha, United States
- University of Nebraska Medical Center — Omaha, United States (Active)
Researchers
- Principal investigator: Lewis, Robert E. — University of Nebraska Medical Center
- Study coordinator: Lewis, Robert E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.