Developing new methods for creating PET imaging agents using fluorine
Official title: Metal-Mediated C-H Radiofluorination for Rapid Access to PET Imaging Agents
Funded at University of Pennsylvania · NIH-11142019 · Data updated 2026-11-12
This study is working on making better and faster PET imaging agents, which are important for helping doctors diagnose and track diseases, so patients can get the care they need more quickly.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $249,000 |
| NIH project number | 4R00EB031564-03 |
| Project ID | NIH-11142019 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include patients undergoing PET scans for disease diagnosis or treatment monitoring.
✕Less likely to help
Patients who do not require PET imaging or are not involved in clinical trials may not benefit from this research.
What this research studies
This research focuses on improving the production of PET imaging agents, which are crucial for diagnosing and monitoring diseases. By utilizing innovative zinc-mediated and metal-free methods for radiofluorination, the project aims to create these agents more efficiently and reliably. This could lead to faster access to essential imaging tools that help in evaluating drug effectiveness and enhancing clinical trials. The approach seeks to address current limitations in the synthesis of fluorine-18 labeled compounds, which are vital for advanced medical imaging.
Why it matters
Potential benefit: If successful, this research could significantly enhance the availability and effectiveness of PET imaging agents for patients.
How similar studies have gone: Previous research has shown promise in improving radiolabeling techniques, but this specific approach is innovative and not widely tested.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Wright, Jay Samuel — University of Pennsylvania
- Study coordinator: Wright, Jay Samuel
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.