Developing MRI-compatible tools for diagnosing and treating heart diseases
Official title: MR-compatible Devices for the Diagnosis and Treatment of Cardiomyopathies
Funded at Johns Hopkins University · NIH-10918188 · Data updated 2026-11-12
This study is working on better ways to take pictures of the heart using MRI, so doctors can more easily diagnose and treat heart problems, especially in kids and adults with certain heart diseases, without needing to do more invasive procedures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | August 20, 2021 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $764,660 |
| NIH project number | 5R01HL157740-04 |
| Project ID | NIH-10918188 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with cardiomyopathies, particularly children and adults who may require heart transplantation or have non-ischemic cardiomyopathies.
✕Less likely to help
Patients with stable heart conditions that do not require invasive diagnostic procedures may not benefit from this research.
What this research studies
This research focuses on improving cardiac magnetic resonance (CMR) imaging techniques to better diagnose and treat heart conditions, particularly cardiomyopathies. It aims to create non-invasive, MRI-compatible devices that can be visualized during procedures like endomyocardial biopsy (EMB), which is currently limited by the use of ferrous materials. By enhancing the accuracy of these procedures, the research seeks to reduce the need for more invasive methods and improve patient outcomes, especially for those with patchy heart diseases. The study will involve both adult and pediatric populations, addressing a significant health issue related to heart failure.
Why it matters
Potential benefit: If successful, this research could lead to safer and more accurate diagnostic procedures for patients with heart diseases, reducing the risks associated with invasive biopsies.
How similar studies have gone: Previous research has shown promise in using non-invasive imaging techniques for heart disease diagnosis, but this specific approach with MRI-compatible devices is relatively novel.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Kraitchman, Dara L — Johns Hopkins University
- Study coordinator: Kraitchman, Dara L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.