Developing an open-source system for nerve stimulation to treat chronic constipation.
OpenNerve Platform for Chronic Constipation.
This study is testing a new, flexible device that helps stimulate nerves to treat chronic constipation, aiming to provide patients with a more effective and affordable treatment option.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11080155 on NIH RePORTER |
What this research studies
This research focuses on creating an open-architecture and open-source implantable system designed for autonomic nerve stimulation, specifically targeting chronic constipation. By validating this system in large animals, the project aims to overcome existing barriers in bioelectronic medicine, such as high costs and limited adaptability of current technologies. Patients may benefit from a more effective and accessible treatment option for chronic constipation through this innovative approach. The research will involve testing the system's functionality and effectiveness in stimulating the sacral nerve.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic constipation who may benefit from neuromodulation therapies.
Not a fit: Patients with constipation caused by non-neurological factors or those who do not respond to nerve stimulation therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide patients with a novel and effective treatment option for chronic constipation.
How similar studies have performed: While the approach of using open-source systems for nerve stimulation is relatively novel, similar bioelectronic therapies have shown promise in other areas of treatment.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Meng, Ellis — University of Southern California
- Study coordinator: Meng, Ellis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.