Developing a new treatment for preeclampsia

Advancing a novel therapy for preeclampsia

NIH-funded research Larix Bioscience, LLC · NIH-10478384

This study is looking at a new way to help women with severe preeclampsia by testing a medication called Digibind to see if it can improve their health during pregnancy.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionLarix Bioscience, LLC NIH-funded
Lab location1 site (Sunnyvale, United States)
Project IDNIH-10478384 on NIH RePORTER

What this research studies

This research focuses on creating a novel therapy for preeclampsia, a serious pregnancy complication characterized by high blood pressure and protein in the urine. The approach involves investigating the role of an endogenous substance known as marinobufagenin, which is believed to contribute to the condition. The study aims to evaluate the effectiveness of Digibind, an existing medication, in improving outcomes for patients with severe preeclampsia. By targeting the underlying mechanisms of the disease, the research hopes to provide a more effective treatment option for affected women.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant women diagnosed with severe preeclampsia.

Not a fit: Patients who are not pregnant or those with mild preeclampsia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a new therapy that significantly improves the health outcomes for pregnant women suffering from preeclampsia.

How similar studies have performed: Previous clinical trials have shown promising results using similar approaches, indicating potential for success in this area.

Where this research is happening

Sunnyvale, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.