Developing a new imaging technique for brain tumors.
Official title: MR Fingerprinting based Quantitative Imaging and Analysis Platform (MRF-QIA) for brain tumors.
Funded at Case Western Reserve University · NIH-11005736 · Data updated 2026-11-12
This study is testing a new MRI technique called MR Fingerprinting that helps doctors get clearer and more consistent pictures of brain tumors, especially aggressive ones like Glioblastomas, to better plan personalized treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $501,133 |
| NIH project number | 5R01CA269604-03 |
| Project ID | NIH-11005736 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with brain tumors, especially those with Glioblastomas.
✕Less likely to help
Patients with non-cancerous brain conditions or those without brain tumors may not benefit from this research.
What this research studies
This research focuses on creating a quantitative imaging platform called MR Fingerprinting (MRF) that aims to improve the accuracy and reproducibility of MRI scans for brain tumors. By providing detailed and standardized measurements of tissue properties, this approach seeks to enhance the characterization of brain tumors, particularly aggressive types like Glioblastomas. The goal is to generate reliable tumor infiltration maps that can inform personalized treatment strategies, including radiation therapy and neurosurgery. This innovative imaging technique could significantly streamline the analysis process and improve clinical outcomes for patients with brain tumors.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and tailored treatment plans for patients with brain tumors.
How similar studies have gone: Previous research has shown promise in using quantitative imaging techniques, suggesting that this approach could lead to significant advancements in brain tumor imaging.
Where this research is happening
-
Case Western Reserve University
Cleveland, United States Active
Researchers
- Principal investigator: Ma, Dan — Case Western Reserve University
- Study coordinator: Ma, Dan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.