Developing a model to improve brain stimulation techniques for better treatment of neurological disorders
CRCNS Research Proposal: Collaborative Research: US-German Collaboration toward a biophysically principled network model of transcranial magnetic stimulation (TMS)
This study is working on improving a safe brain treatment called transcranial magnetic stimulation (TMS) to help people with brain disorders by making it more effective, so patients can have better options for managing their conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10877867 on NIH RePORTER |
What this research studies
This research focuses on enhancing transcranial magnetic stimulation (TMS), a non-invasive technique used to modulate brain activity, which is currently FDA-approved for various brain disorders but has inconsistent effectiveness. By creating a detailed network model that integrates electric field simulations with neuron and molecular simulations, the research aims to refine stimulation protocols. This could lead to more effective treatments for conditions related to brain activity imbalances. Patients may benefit from improved therapeutic options as a result of this innovative approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from neurological or psychiatric conditions that may benefit from enhanced TMS protocols.
Not a fit: Patients with conditions not related to brain activity or those who do not respond to TMS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for neurological and psychiatric disorders, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in improving TMS efficacy through advanced modeling techniques, indicating potential for success in this approach.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Opitz, Alexander — University of Minnesota
- Study coordinator: Opitz, Alexander
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.