Detecting colorectal cancer using exosomal biomarkers
Exosomal Biomarkers for the Noninvasive Detection of Colorectal Cancer
This study is looking for a gentle way to spot colorectal cancer by checking tiny particles called exosomes in your body, which can show signs of cancer without needing invasive tests like a colonoscopy, helping to catch the disease early and improve treatment outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Beckman Research Institute/city of Hope NIH-funded |
| Lab location | 1 site (Duarte, United States) |
| Project ID | NIH-10669178 on NIH RePORTER |
What this research studies
This research focuses on developing a noninvasive method for detecting colorectal cancer (CRC) by analyzing exosomal biomarkers. Exosomes, which are small vesicles released by cells, carry molecular information that can indicate the presence of cancer. The study aims to identify specific microRNAs within these exosomes that are altered in CRC, providing a potential alternative to invasive screening methods like colonoscopy. By improving early detection, the research seeks to enhance patient outcomes and reduce mortality associated with colorectal cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for colorectal cancer, particularly those with a family history or other risk factors.
Not a fit: Patients who have already been diagnosed with advanced colorectal cancer may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to a simple and noninvasive test for early detection of colorectal cancer, making screening more accessible and effective.
How similar studies have performed: Previous research has shown promise in using exosomal biomarkers for cancer detection, indicating that this approach may be viable.
Where this research is happening
Duarte, United States
- Beckman Research Institute/city of Hope — Duarte, United States (Active)
Researchers
- Principal investigator: Goel, Ajay — Beckman Research Institute/city of Hope
- Study coordinator: Goel, Ajay
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.