NIH-funded research R01 grant

Deep Learning Retina Tool to Find Early Alzheimer’s

Official title: Deep Learning-Based Retinal Imaging Screening Tool for Preclinical Alzheimer’s Disease

Funded at Arizona State University-Tempe Campus · NIH-11391547 · Data updated 2026-11-12

A new AI-based retinal imaging tool aims to help identify people at risk for Alzheimer’s before symptoms appear using a quick, noninvasive eye scan.

More s Disease research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionArizona State University-Tempe Campus
NIH-funded
Lab location1 site (Scottsdale, United States)
Project startAugust 15, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$655,917
NIH project number1R01AG087633-01A1
Project IDNIH-11391547 on NIH RePORTER

Who could benefit from this research

Could help

Adults at risk for Alzheimer’s or with concerns about preclinical AD who are undergoing retinal imaging.

Less likely to help

Individuals without risk factors or imaging data may not benefit from this specific tool.

What this research studies

This project uses deep learning to analyze routine eye photos and detect signs linked to early Alzheimer’s disease. By focusing on the retina, the researchers hope to find biomarkers that reflect brain changes without expensive or invasive tests. If successful, the tool could be used in clinics to flag individuals who may benefit from earlier monitoring or intervention. The study will build and test AI methods on retinal images from adults, with attention to image quality and real-world usability.

Why it matters

Potential benefit: If the tool works, it could enable earlier identification of people at risk for Alzheimer’s through a simple eye exam.

How similar studies have gone: Deep learning approaches have improved retinal image analysis for other conditions and show promise for AD-related biomarkers in the retina.

Where this research is happening

  • Arizona State University-Tempe Campus
    Scottsdale, United States
    Active

Researchers

  • Principal investigator: Wang, Yalin — Arizona State University-Tempe Campus
  • Study coordinator: Wang, Yalin

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.