CureGN-Penn Pediatric/Adult Glomerular Disease Registry and Cohort
Official title: CureGN-Penn PCC
Funded at University of Pennsylvania · NIH-11548465 · Data updated 2026-11-12
A large, long-term study from CureGN to better understand how common kidney diseases affect both kids and adults and to help others in the future through shared data and samples.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 16, 2013 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $28,356 |
| NIH project number | 3U01DK100846-14S3 |
| Project ID | NIH-11548465 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults and children diagnosed with MCD, FSGS, IgAN, or MN who are or have been enrolled in CureGN and consent to ongoing data and biospecimen collection.
✕Less likely to help
Individuals not affected by the specified glomerular diseases may not directly benefit from this study.
What this research studies
This project builds on CureGN’s large, ongoing registry of patients with diseases like MCD, FSGS, IgAN, and MN. It collects biospecimens, clinical information, and patient-reported outcomes across many sites to enable high-quality research into disease causes, progression, and response to therapy. Participants contribute data and samples during routine care and follow-up visits, with a focus on longitudinal insights. Researchers use this resource to perform mechanistic and translational studies that could lead to improved diagnostics and treatments for glomerular diseases. The study emphasizes collaboration among patients, clinicians, and researchers to accelerate discoveries that benefit both children and adults with these conditions.
Why it matters
Potential benefit: Potential for improved understanding, prognosis, and treatment options for pediatric and adult glomerular diseases.
How similar studies have gone: CureGN has already recruited thousands of participants and produced valuable observational data and biospecimen resources used in multiple investigations.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Holzman, Lawrence B. — University of Pennsylvania
- Study coordinator: Holzman, Lawrence B.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.