CureGN-Penn Pediatric and Adult Glomerulonephropathy Registry
Official title: CureGN-Penn PCC
Funded at University of Pennsylvania · NIH-11548463 · Data updated 2026-11-12
A large, long-term study following adults and children with glomerular diseases to understand how these conditions develop and respond to treatment.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 16, 2013 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $25,645 |
| NIH project number | 3U01DK100846-14S1 |
| Project ID | NIH-11548463 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults and children with primary glomerular diseases such as MCD, FSGS, IgAN, or MN who are enrolled through participating clinical centers.
✕Less likely to help
Patients not diagnosed with these specific glomerular diseases or not eligible for follow-up may not benefit directly.
What this research studies
This project builds on CureGN to enroll and observe patients with MCD, FSGS, IgAN, and MN across multiple sites, collecting biospecimens, clinical data, and patient-reported outcomes over time. Researchers aim to uncover disease paths and responses to therapies so future care can be more personalized. Participants may undergo regular follow-ups and provide samples that help link clinical information with biology. The effort brings together patients, clinicians, researchers, and patient groups to advance knowledge about these kidney diseases.
Why it matters
Potential benefit: If successful, findings could lead to better diagnosis, monitoring, and personalized treatments for glomerular diseases in both children and adults.
How similar studies have gone: Previous CureGN efforts have recruited thousands of participants and generated valuable biospecimens and outcomes for mechanistic and translational studies.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Holzman, Lawrence B. — University of Pennsylvania
- Study coordinator: Holzman, Lawrence B.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.