NIH-funded research NIH-funded research

CT-DPACC for AMP SCZ: Coordinating Big Data to Understand and Prevent Schizophrenia

Official title: Clinical Trial Data Processing, Analysis, and Coordination Center (CT-DPACC) for Accelerating Medicines Partnership Schizophrenia (AMP SCZ) Project

Funded at Brigham and Women's Hospital · NIH-11533656 · Data updated 2026-11-12

A nationwide effort will process and analyze data from a large schizophrenia study to help scientists find patterns that could prevent psychosis in young people at risk.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startJune 17, 2024
Project endMay 31, 2029
Funding year2026
Award (this year)$119,268
NIH project number3U24MH137171-03S1
Project IDNIH-11533656 on NIH RePORTER

Who could benefit from this research

Could help

Young people at clinical high risk for psychosis or in the early stages of psychosis who may contribute data or be candidates for future trials.

Less likely to help

Patients not enrolled in or directly related to the AMP SCZ data-sharing and biomarker efforts may not receive immediate clinical benefits.

What this research studies

This project provides a centralized data processing and coordination center for AMP SCZ, handling large-scale data from multiple studies to enable deeper insights. It focuses on harmonizing data, applying advanced bioinformatics methods, and coordinating researchers to accelerate discovery of biomarkers and drug-development tools. By making data more usable and comparable, clinicians and patients could benefit from faster progress toward better prevention and treatment strategies for psychosis risk.

Why it matters

Potential benefit: If successful, the work could speed up identification of early warning signs and improve prevention strategies for psychosis.

How similar studies have gone: Prior efforts have shown that standardized data protocols and robust biomarkers can improve drug development and risk stratification in psychiatric conditions.

Where this research is happening

  • Brigham and Women's Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Shenton, Martha E. — Brigham and Women's Hospital
  • Study coordinator: Shenton, Martha E.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.