Creating stem cell-based vascular grafts for emergency surgeries
Readily Available Stem Cell-Based Vascular Grafts for Emergent Surgical Care
This study is working on a new type of blood vessel replacement made from stem cells to help people who have serious injuries, like from accidents, when regular options aren't available, making it easier and safer to get the care they need quickly.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10636647 on NIH RePORTER |
What this research studies
This research focuses on developing a new type of vascular graft made from stem cells to help patients who have suffered severe vascular trauma, such as from accidents or blast injuries. The goal is to create a readily available graft that can be used in emergency situations when traditional options, like using a patient's own veins, are not feasible. The approach involves engineering vascular grafts that can be quickly produced and are strong enough to withstand the body's conditions. By using stem cells, the researchers aim to overcome the limitations of current graft options, which can be hindered by infection risks and variability in donor tissues.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have experienced severe vascular trauma and require immediate surgical intervention.
Not a fit: Patients with vascular injuries that do not require grafting or those who are not surgical candidates may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new, reliable option for patients needing vascular repair during emergencies, potentially saving limbs and lives.
How similar studies have performed: While the concept of using stem cells for vascular grafts is being explored, this specific approach is innovative and has not been widely tested in emergency surgical contexts.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Qyang, Yibing — Yale University
- Study coordinator: Qyang, Yibing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.