Creating light-sensitive tools to study brain networks
Official title: Development of Light Triggered Molecular Tools Critical for Understanding the Brain's Network
Funded at Florida Institute of Technology · NIH-11043886 · Data updated 2026-11-12
This study is exploring new ways to use light to help scientists understand how brain cells communicate, which could lead to better treatments for conditions like dementia and epilepsy.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida Institute of Technology NIH-funded |
| Lab location | 1 site (Melbourne, United States) |
| Project start | December 16, 2024 |
| Project end | December 15, 2027 |
| Funding year | 2025 |
| Award (this year) | $434,610 |
| NIH project number | 9R15MH139078-03 |
| Project ID | NIH-11043886 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals affected by brain disorders, including dementia and epilepsy.
✕Less likely to help
Patients with non-neurological conditions or those not affected by brain disorders may not benefit from this research.
What this research studies
This research focuses on developing innovative molecular tools that can be activated by light to better understand the complex networks of neurons in the brain. By collaborating with neuroscientists, the project aims to manipulate specific neuronal connections with high precision, particularly investigating the role of calcium ions in learning and memory. The approach involves using photo switchable chelating systems that release active compounds when exposed to light, allowing for targeted studies of brain function. This could lead to breakthroughs in understanding brain disorders such as dementia and epilepsy.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of brain disorders and lead to new therapeutic strategies.
How similar studies have gone: Other research has shown promise in using light-activated tools for neuroscience, indicating potential for success in this novel approach.
Where this research is happening
-
Florida Institute of Technology
Melbourne, United States Active
Researchers
- Principal investigator: Nesnas, Nasri — Florida Institute of Technology
- Study coordinator: Nesnas, Nasri
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.