Controlling cellular aging using engineered genetic systems
Engineered genetic clocks for control of cellular aging
This study is exploring ways to slow down the aging of cells using advanced techniques, starting with yeast, to help us understand how we might improve health and treat age-related diseases like cancer and Alzheimer's in people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11052456 on NIH RePORTER |
What this research studies
This research investigates how to manipulate the aging process of cells by using synthetic biology and computational modeling. The focus is on understanding the mechanisms of cellular aging in yeast, which can provide insights applicable to human aging and age-related diseases. By engineering specific gene networks, the researchers aim to slow down the aging process and improve cellular health. This innovative approach could lead to breakthroughs in treating conditions like cancer and neurodegenerative disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing age-related diseases or conditions, particularly those related to cellular aging.
Not a fit: Patients with acute or non-age-related conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that slow down cellular aging and improve health outcomes for age-related diseases.
How similar studies have performed: Other research in synthetic biology has shown promise in manipulating biological processes, suggesting potential success for this novel approach.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Hao, Nan — University of California, San Diego
- Study coordinator: Hao, Nan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.