Connecting metabolism with cellular changes using advanced imaging techniques
Official title: Developing multiparametric fluorescence microscopy to connect metabolism with cellular manipulations
Funded at Georgetown University · NIH-10938773 · Data updated 2026-11-12
This study is looking at how different factors affect the way cells work and interact with each other, using special imaging techniques to see these changes in real-time, which could help us understand more about cell behavior.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgetown University NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project start | September 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $390,000 |
| NIH project number | 1R35GM154815-01 |
| Project ID | NIH-10938773 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve metabolic dysregulation or cellular manipulation, such as cancer or metabolic disorders.
✕Less likely to help
Patients with stable metabolic conditions that do not require cellular manipulation may not benefit from this research.
What this research studies
This research focuses on understanding how metabolic changes in cells are influenced by various internal and external factors. By using advanced fluorescence microscopy techniques, the project aims to simultaneously observe and correlate multiple cellular properties, such as protein diffusion and membrane fluidity, at a very high resolution. This innovative approach will allow researchers to investigate how altering one cellular property can affect others, providing deeper insights into cellular behavior and interactions. The ultimate goal is to develop a comprehensive imaging framework that can quantify these interactions in real-time.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of cellular metabolism and its implications for various diseases, potentially guiding new therapeutic strategies.
How similar studies have gone: While the approach of combining multiple imaging modalities is innovative, similar methodologies have shown promise in other areas of cellular research, indicating potential for success.
Where this research is happening
-
Georgetown University
Washington, United States Active
Researchers
- Principal investigator: Ranjit, Suman — Georgetown University
- Study coordinator: Ranjit, Suman
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.