Comparing the effects of single versus multiple arterial grafts on quality of life after heart surgery

Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: Quality of Life (ROMA:QOL)

NIH-funded research Weill Medical Coll of Cornell Univ · NIH-10829421

This study looks at how different types of heart surgery for patients with multiple blocked arteries affect their quality of life and symptoms over five years, helping to find out which surgical method is better for improving everyday well-being.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWeill Medical Coll of Cornell Univ NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10829421 on NIH RePORTER

What this research studies

This research investigates how coronary artery bypass graft (CABG) surgery, which is commonly performed for patients with multi-vessel coronary heart disease, affects patients' quality of life and symptom burden. It compares the outcomes of using single arterial grafts versus multiple arterial grafts in a large group of participants over five years. By utilizing validated questionnaires, the study aims to provide insights into how these surgical options impact patients' daily lives and overall well-being. The research is part of a larger trial that seeks to determine the best surgical approach for improving patient outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with multi-vessel coronary heart disease who are scheduled to undergo CABG surgery.

Not a fit: Patients who do not have coronary heart disease or those who are not candidates for CABG surgery may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved surgical practices that enhance the quality of life for patients undergoing heart surgery.

How similar studies have performed: Previous research has shown promising results in comparing surgical techniques for heart disease, suggesting that this approach could yield valuable insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Coronary Diseaseatherosclerotic heart diseasecoronary disorderCoronary heart disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.