Comparative-Effectiveness of Carotid Revascularization Procedures
Official title: Comparative-Effectiveness of Procedures for Carotid Revascularization
Funded at Dartmouth-Hitchcock Clinic · NIH-11325374 · Data updated 2026-11-12
This grant explores how well different carotid artery procedures work to lower stroke risk for people with narrowed carotid arteries.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth-Hitchcock Clinic NIH-funded |
| Lab location | 1 site (Lebanon, United States) |
| Project start | June 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $146,880 |
| NIH project number | 5K08HL165087-04 |
| Project ID | NIH-11325374 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with carotid artery stenosis considering revascularization and able to participate in follow-up.
✕Less likely to help
Patients not eligible for revascularization or those who choose non-procedural medical management may not benefit.
What this research studies
The project focuses on carotid artery stenosis and the real-world outcomes of three procedures: carotid endarterectomy (CEA), transfemoral carotid artery stenting (TF-CAS), and transcarotid artery revascularization (TCAR). It aims to compare safety, effectiveness, and long-term results to guide which procedure may be best for different patients. Researchers will use clinical data and patient-follow-up to understand how each option affects stroke risk, recovery, and quality of life in diverse populations. The work is led by Dartmouth-Hitchcock Clinic and involves patients who may be candidates for carotid revascularization.
Why it matters
Potential benefit: If successful, the findings could help patients and clinicians choose the most effective procedure with the lowest risk of stroke and complications.
How similar studies have gone: Prior trials have compared CEA and TF-CAS with established results, but TCAR evidence is limited and growing.
Where this research is happening
-
Dartmouth-Hitchcock Clinic
Lebanon, United States Active
Researchers
- Principal investigator: Columbo, Jesse a — Dartmouth-Hitchcock Clinic
- Study coordinator: Columbo, Jesse a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.