NIH-funded research NIH-funded research

Common Fund Knowledge Center: turning big biomedical data into clear, usable knowledge

Official title: The Common Fund Knowledge Center (CFKC): providing scientifically valid knowledge from the Common Fund Data Ecosystem to the biomedical research community

Funded at Broad Institute, INC. · NIH-11533207 · Data updated 2026-11-12

A project to make NIH CF datasets easy to find and trust by presenting them as clear, scientifically valid knowledge that researchers can use with confidence.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBroad Institute, INC.
NIH-funded
Lab location1 site (Cambridge, United States)
Project startSeptember 18, 2023
Project endSeptember 17, 2028
Funding year2026
Award (this year)$420,000
NIH project number3OT2OD036440-01S3
Project IDNIH-11533207 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable to a specific patient group; design focuses on researchers and data users.

Less likely to help

Patients do not participate directly in this grant, and outcomes are research-tool oriented.

What this research studies

This project will convert large NIH Common Fund datasets into a knowledge graph that emphasizes scientifically valid findings and expert analyses, making complex data easier for researchers to understand. It includes developing a user-friendly portal with visuals that highlight context and uncertainty, rather than generic graph traversal. The goal is to help researchers from many disciplines access trustworthy conclusions drawn from Big Data in biomedicine.

Why it matters

Potential benefit: If successful, scientists will access more reliable, context-rich data to advance biomedical research more efficiently.

How similar studies have gone: Prior experiences with knowledge graphs in biomedicine show promise when emphasizing validity and context, though this project is a novel integration for CF data.

Where this research is happening

  • Broad Institute, INC.
    Cambridge, United States
    Active

Researchers

  • Principal investigator: Flannick, Jason — Broad Institute, INC.
  • Study coordinator: Flannick, Jason

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.