Combined effects of PrEP and HIV stigma on PrEP adherence in youth at risk for HIV
Official title: Combined Effects of PrEP and HIV Stigma on PrEP Adherence: Psychosocial Pathways among Youth at Risk for HIV
Funded at Florida State University · NIH-11470901 · Data updated 2026-11-12
A small, patient-friendly study will explore how stigma around PrEP and HIV affects whether at-risk youth stick with PrEP, using real data from teens and young adults.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Florida State University NIH-funded |
| Lab location | 1 site (Tallahassee, United States) |
| Project start | September 25, 2026 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $154,000 |
| NIH project number | 1R03NR022593-01A1 |
| Project ID | NIH-11470901 on NIH RePORTER |
Who could benefit from this research
✓Could help
Youth and young adults at risk for HIV who are considering or using PrEP.
✕Less likely to help
Youth not considering PrEP or not at risk for HIV may not benefit from this study.
What this research studies
This project uses data from the P3 trial to understand how different kinds of stigma alter PrEP adherence among youth at risk for HIV. Researchers will identify patterns of stigma and examine how these patterns relate to self-reported adherence and blood-based adherence measures. They will also test whether factors like PrEP confidence, perceived risk, and social support explain these relationships. The study uses statistical methods to group participants by stigma profiles and to test mediation pathways that lead to better or worse adherence.
Why it matters
Potential benefit: Understanding stigma pathways could lead to targeted support strategies to improve PrEP adherence in youth at risk for HIV.
How similar studies have gone: Previous work shows stigma can affect PrEP use; this study builds on existing findings with a larger, diverse youth sample.
Where this research is happening
-
Florida State University
Tallahassee, United States Active
Researchers
- Principal investigator: Yigit, Ibrahim — Florida State University
- Study coordinator: Yigit, Ibrahim
Related research
Other NIH-funded projects on the same topics.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
-
Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
-
Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
-
Participatory system dynamics to improve PrEP access in the Bronx
A community-driven project in the Bronx will use system dynamics to identify practical ways to help people at risk for HIV start and stay on PrEP.
-
TB PrEP: Bringing HIV prevention to households affected by TB in Uganda
Aims to help people in households with TB in Uganda access HIV PrEP as part of a combined prevention approach.
-
CARES: A practical program to help adolescent girls and young women use PrEP in Africa
A program called CARES helps young women in South Africa and Zimbabwe use different PrEP options better, with counseling, reminders, and options for support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.