NIH-funded research Career grant

Childhood adversity and teen substance use: how mood and feelings influence risky choices

Official title: Childhood adversity and substance use: Integrating laboratory and ecological approaches to understand the role of affect

Funded at Miriam Hospital · NIH-11392988 · Data updated 2026-11-12

A psychologist is studying how tough early life experiences affect teens’ chances of using substances, focusing on how feelings and mood may link adversity to later use.

More Substance Use research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionMiriam Hospital
NIH-funded
Lab location1 site (Providence, United States)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$186,484
NIH project number5K08DA056697-05
Project IDNIH-11392988 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents and young adults who have experienced childhood adversity and are at risk for substance use.

Less likely to help

Teens without exposure to adversity or those not at risk for substance use may see limited direct benefit.

What this research studies

This grant supports a career development path for a clinician-scientist who will study how affect (feelings) shapes the link between childhood adversity and substance use in adolescents. It uses a mix of lab techniques (like eye tracking and physiological measures) and real-world observation to understand why some teens with ACEs start or avoid using substances. The goal is to build stronger, evidence-based approaches to prevention and intervention that consider emotional processes in adolescence. Training includes mentorship, courses, and hands-on experience to foster independence as a researcher focused on adolescent risk and resilience.

Why it matters

Potential benefit: If successful, the work could lead to personalized prevention strategies that address emotional factors to reduce teen substance use.

How similar studies have gone: Prior work has linked ACEs to higher risk of substance use, with growing evidence that affective processes mediate this risk.

Where this research is happening

  • Miriam Hospital
    Providence, United States
    Active

Researchers

  • Principal investigator: Brown, Shaquanna a. — Miriam Hospital
  • Study coordinator: Brown, Shaquanna a.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.