Center to speed up proven health improvements for people with serious mental illness
Official title: Center to Accelerate Translation of Interventions to Decrease Premature Mortality in Persons with Serious Mental Illness
Funded at Johns Hopkins University · NIH-11421405 · Data updated 2026-11-12
A Johns Hopkins-led center aims to bring already-proven heart-health interventions to adults with serious mental illness to cut their early deaths from heart disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | August 15, 2018 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $2,454,379 |
| NIH project number | 5P50MH115842-07 |
| Project ID | NIH-11421405 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (21+) with serious mental illness who are at risk for cardiovascular disease and can participate in community or clinical settings.
✕Less likely to help
Some individuals may not directly benefit if they have contraindications to proposed interventions or face barriers to access.
What this research studies
This program focuses on people 21 and older with serious mental illness who are at high risk for cardiovascular disease. It uses collaborative, cross-disciplinary methods to translate and scale up effective strategies for improving diet, activity, smoking cessation, and other heart-healthy behaviors. The center will engage patients, clinicians, and community partners to tailor and implement practical interventions in real-world settings, while developing new study methods to accelerate adoption. The goal is to reduce premature mortality by making proven heart-health approaches widely available to this underserved population.
Why it matters
Potential benefit: If successful, the project could lower the risk of heart disease and early death for people with serious mental illness by delivering effective, real-world interventions.
How similar studies have gone: prior programs have shown benefits when interventions are implemented in real-world settings, though scaling to this population remains challenging.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Daumit, Gail L. — Johns Hopkins University
- Study coordinator: Daumit, Gail L.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.