Center for Undiagnosed Diseases using AI and big data
Official title: Vanderbilt Center of Excellence for Undiagnosed Disease (VCEUD)
Funded at Vanderbilt University Medical Center · NIH-11538401 · Data updated 2026-11-12
A Vanderbilt-led initiative uses AI and data science to help people with mysterious medical conditions get clearer diagnoses and better care.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | September 1, 2014 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $167,174 |
| NIH project number | 3U01NS134349-13S1 |
| Project ID | NIH-11538401 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with unexplained symptoms or diagnostic challenges who have exhausted standard testing.
✕Less likely to help
Patients whose conditions are already well-understood or who do not meet the criteria for the undiagnosed diseases program.
What this research studies
This project brings together clinicians, geneticists, and data scientists to accelerate diagnosis for patients with undiagnosed diseases. It uses advanced AI language models and bioinformatics tools to analyze patient data across multiple tiers of evaluation. By connecting clinical findings with large-scale databases and AI analyses, the center aims to improve understanding and management of complex conditions. If successful, it could shorten the journey to a diagnosis and inform more personalized treatment plans.
Why it matters
Potential benefit: Potentially faster, more accurate diagnoses and improved care for people with undiagnosed diseases.
How similar studies have gone: Prior undiagnosed disease initiatives have shown promise in delivering new diagnoses through integrated data analysis and expert review.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Hamid, Rizwan — Vanderbilt University Medical Center
- Study coordinator: Hamid, Rizwan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.