NIH-funded research NIH-funded research

Center for Multiscale Immune Systems Modeling

Funded at Duke University · NIH-11583652 · Data updated 2026-11-12

A Duke University team is building a multi-scale modeling center to better understand and predict immune responses to infections like COVID-19 using advanced AI and sharing data and models.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startJune 13, 2025
Project endMay 31, 2030
Funding year2026
Award (this year)$915,980
NIH project number3U54AI191253-02S1
Project IDNIH-11583652 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable; this is a modeling center, not a patient enrollment study.

Less likely to help

Direct participation by patients is not part of this center’s activities.

What this research studies

This center brings together experts to develop AI-augmented models of how immune systems respond to viral infections at multiple biological scales. It includes an Administrative Core, a Community Development and Education Core, a Model and Data Sharing Core, and three Research Projects that connect molecular to organism-level processes. The project aims to create an informatics infrastructure for data-model integration, share resources across researchers, and educate the next generation of scientists in IID modeling. Through collaborative efforts, the center seeks to enable faster, more accurate predictions that could inform public health decisions during outbreaks.

Why it matters

Potential benefit: If successful, the work could lead to improved understanding and prediction of immune responses, helping to guide treatment and prevention strategies during infectious outbreaks.

How similar studies have gone: Previous modeling centers have shown that multi-scale AI models can improve outbreak predictions and inform decisions.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Chan, Cliburn C — Duke University
  • Study coordinator: Chan, Cliburn C

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.