CCASAnet: HIV care and outcomes across the Americas
Official title: Caribbean, Central, and South America network for HIV Epidemiology (CCASAnet)
Funded at Vanderbilt University Medical Center · NIH-11541266 · Data updated 2026-11-12
A large network across the Americas studies how HIV care and health outcomes look in real-world settings to improve care for people living with HIV.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | June 15, 2006 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $84,715 |
| NIH project number | 3U01AI069923-22S3 |
| Project ID | NIH-11541266 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with HIV who receive care at CCASAnet participating sites in Argentina, Brazil, Chile, Haiti, Honduras, Mexico, Peru, and the United States.
✕Less likely to help
Individuals not engaged in HIV care or outside CCASAnet sites may not directly benefit from this program.
What this research studies
CCASAnet harmonizes data from HIV clinics in multiple countries to understand how people with HIV are managed in routine care. The program analyzes clinical, statistical, and informatics data to identify gaps in the HIV care continuum, including people lost to follow-up, pregnancy outcomes, and comorbidities. It also develops new biostatistics and informatics methods, supports mentoring, and builds local research capacity. During the current cycle, the network will explore outcomes for adolescents and older adults, as well as how substance use and mental health intersect with HIV and non-communicable diseases. The work is conducted through the Vanderbilt Data Coordinating Center and collaborating sites to generate insights that inform better treatment and prevention strategies across the Americas.
Why it matters
Potential benefit: If successful, the project could improve HIV care quality, retention in care, and management of comorbidities for people living with HIV across the Americas.
How similar studies have gone: This approach builds on established international HIV observational research networks with growing data-driven insights.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Castilho, Jessica L — Vanderbilt University Medical Center
- Study coordinator: Castilho, Jessica L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.