NIH-funded research R01 grant

Cannabis and tobacco co-use in young adults during quit attempts

Official title: The impact of cannabis and tobacco/nicotine product co-use in young adults: Prospective cessation evaluation and substitution

Funded at Medical University of South Carolina · NIH-11391210 · Data updated 2026-11-12

Young adults who use both cannabis and nicotine may have a harder time quitting either one, and this study aims to understand how cannabis affects nicotine cessation.

More Cannabis research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina
NIH-funded
Lab location1 site (Charleston, United States)
Project startSeptember 1, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$606,794
NIH project number5R01CA276066-04
Project IDNIH-11391210 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are young adults (around 18–25) attempting to quit nicotine who also use cannabis.

Less likely to help

Individuals not seeking nicotine cessation or who do not use cannabis may not benefit from this research.

What this research studies

This project follows young adults who are trying to quit nicotine to see how cannabis use influences their quit success and overall treatment outcomes. Researchers will collect behavioral and biochemical data to map how co-use patterns relate to quitting difficulty. Using a behavioral economics framework, the study will explore how cannabis affects decision-making and motivation during cessation efforts.

Why it matters

Potential benefit: If successful, findings could guide personalized strategies to help young adults quit nicotine while considering cannabis use.

How similar studies have gone: Some prior studies suggest cannabis can complicate nicotine cessation, but there are few prospective analyses in youth.

Where this research is happening

  • Medical University of South Carolina
    Charleston, United States
    Active

Researchers

  • Principal investigator: Mcclure, Erin a — Medical University of South Carolina
  • Study coordinator: Mcclure, Erin a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.