NIH-funded research R01 grant

Calories vs. Sweet Taste: How Beverage Branding Shapes Your Habits

Official title: Parsing the Impact of Calories versus Sweet Taste on Beverage Brand Conditioning: A Randomized Controlled Trial

Funded at Monell Chemical Senses Center · NIH-11432601 · Data updated 2026-11-12

A randomized study examines how calories and sweet taste affect how adults respond to a beverage brand and whether daily consumption changes craving for that brand.

More Randomized Controlled Trial research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMonell Chemical Senses Center
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startAugust 1, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$828,937
NIH project number1R01DK149422-01
Project IDNIH-11432601 on NIH RePORTER

Who could benefit from this research

Could help

Adults with or at risk for Adult-Onset Diabetes Mellitus who are willing to participate in a beverage consumption and brain-imaging study.

Less likely to help

Individuals who are unable to participate in MRI scanning or who are not willing to consume the study beverages may not benefit.

What this research studies

This project explores how non-nutritive sweeteners and sugar-sweetened beverages influence real-world eating behavior, focusing on brand- and advertisement-related cues. It uses a randomized controlled design to see if repeated exposure to a specific beverage brand changes people’s motivation to seek that brand, and whether brain signals in the ventral striatum reflect this change. Participants will consume beverages over several weeks and undergo brain imaging and behavioral assessments to separate the effects of taste, calories, and branding. The findings could help explain how marketing and taste shape cravings and intake in adults with obesity risk factors.

Why it matters

Potential benefit: If successful, the work could inform strategies to reduce unhealthy beverage choices and support weight-management efforts.

How similar studies have gone: Previous studies have shown brand- and cue-driven approach behaviors; this work directly tests brand sensitization mechanisms with neural correlates.

Where this research is happening

  • Monell Chemical Senses Center
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Burger, Kyle S. — Monell Chemical Senses Center
  • Study coordinator: Burger, Kyle S.

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.