Brain-wide brain-network scores to understand ADHD heterogeneity
Official title: Brain Wide Associations-Polyneuro Risk Scores to characterize heterogeneity in ADHD
Funded at University of Minnesota · NIH-11363195 · Data updated 2026-11-12
A study based at the University of Minnesota will create and test polyneuro risk scores that link whole-brain network patterns to different ADHD traits in children, aiming to better characterize why ADHD looks different in each child.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | September 10, 2026 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $761,091 |
| NIH project number | 1R01MH140801-01A1 |
| Project ID | NIH-11363195 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children around ages 7 to 9 with ADHD or related attention and self-regulation difficulties.
✕Less likely to help
Children without ADHD or without participating brain-imaging or related assessments may not directly benefit.
What this research studies
This project plans to combine large brain-imaging data with measurements of attention, self-control, and emotion in kids with ADHD to develop comprehensive brain-network scores. Researchers will harmonize methods across datasets and validate the scores in diverse groups to see if they reliably capture ADHD-related brain activity. The goal is to move beyond looking at single brain regions and understand how distributed brain networks relate to cognitive and emotional symptoms. If successful, these scores could help tailor understanding and approaches to individual children.
Why it matters
Potential benefit: If successful, the work could lead to better ways to characterize ADHD in individual children and guide more personalized interventions.
How similar studies have gone: Prior large-scale studies support a distributed-brain network view of ADHD, but harmonization and validation in diverse samples is still needed.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Miranda-Dominguez, Oscar — University of Minnesota
- Study coordinator: Miranda-Dominguez, Oscar
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.