Brain heat and chemical changes in adults with sleep apnea
Official title: Brain Metabolites and Temperature Changes in Obstructive Sleep Apnea Adults
Funded at University of California Los Angeles · NIH-11391289 · Data updated 2026-11-12
This project looks at how obstructive sleep apnea affects brain temperature and chemistry in adults, which could reveal why sleep apnea worsens thinking, mood, and health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | September 6, 2024 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $687,431 |
| NIH project number | 5R01HL174651-03 |
| Project ID | NIH-11391289 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults aged 21 and older with obstructive sleep apnea or related acquired brain injury features.
✕Less likely to help
People without sleep apnea or related brain injury conditions may not benefit from this study.
What this research studies
If you have sleep apnea, this study would examine brain changes that happen because of intermittent oxygen loss during sleep. Researchers will explore brain temperature, metabolites, and antioxidant levels using noninvasive imaging and measurements. The goal is to understand where and how brain injury occurs so future treatments can protect brain health in people with sleep apnea.
Why it matters
Potential benefit: Discoveries could lead to better ways to prevent or lessen brain injury and cognitive problems in sleep apnea.
How similar studies have gone: Previous work has linked sleep apnea to brain changes, but this project aims to map regional brain temperature and metabolites in detail.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Kumar, Rajesh — University of California Los Angeles
- Study coordinator: Kumar, Rajesh
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.