Bloodstream yeast infection test directly from blood
Official title: Bloodstream infection detection directly on whole blood
Funded at Scanogen, INC. · NIH-11352556 · Data updated 2026-11-12
A new automated test kit can detect most yeasts causing bloodstream infections directly from a patient’s blood to help doctors start the right antifungal treatment sooner.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Scanogen, INC. NIH-funded |
| Lab location | 1 site (Baltimore, UNITED STATES) |
| Project start | June 1, 2016 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,000,000 |
| NIH project number | 5R44AI124871-07 |
| Project ID | NIH-11352556 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with suspected or confirmed yeast bloodstream infections or those at high risk due to symptoms or hospital admission.
✕Less likely to help
Patients with non-yeast infections or those whose infection is not detected by the SMOLT-Yeast assay may not benefit.
What this research studies
This project aims to finish an automated instrument and SMOLT-Yeast assay that can identify yeast directly in whole blood without waiting for blood cultures. The test uses a disposable cartridge and a desktop device to deliver rapid results from a patient's blood sample. If successful, it could shorten the time to diagnosis from days to hours and improve survival for people with yeast bloodstream infections. The approach builds on previous milestones and clinical testing to ensure accuracy in real-world samples.
Why it matters
Potential benefit: If successful, patients could receive faster, more accurate diagnoses and earlier antifungal therapy, potentially reducing deaths from yeast bloodstream infections.
How similar studies have gone: Previous work has demonstrated analytical and clinical performance, suggesting this approach is promising but may require broader validation.
Where this research is happening
-
Scanogen, INC.
Baltimore, United States Active
Researchers
- Principal investigator: Celedon, Alfredo Andres — Scanogen, INC.
- Study coordinator: Celedon, Alfredo Andres
Related research
Other NIH-funded projects on the same topics.
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Bloodstream infection detection directly on whole blood
A new automated test detects yeast infections in a patient’s blood quickly, helping doctors start the right antifungal treatment sooner.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.