Bloodstream infection detection directly on whole blood
Funded at Scanogen, INC. · NIH-11416610 · Data updated 2026-11-12
A new automated test detects yeast infections in a patient’s blood quickly, helping doctors start the right antifungal treatment sooner.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Scanogen, INC. NIH-funded |
| Lab location | 1 site (Baltimore, UNITED STATES) |
| Project start | September 17, 2025 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $972,243 |
| NIH project number | 5SB1AI192001-02 |
| Project ID | NIH-11416610 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with suspected bloodstream yeast infections or those at high risk for candidemia.
✕Less likely to help
If an infection is not caused by yeast or if the patient’s blood sample quality is poor, benefits may be limited.
What this research studies
This project builds on an automated platform that tests a patient’s whole blood for yeast without traditional blood cultures. Using the SMOLT method, a disposable cartridge and desktop instrument process the sample to identify multiple yeast species, including Candida auris, with high accuracy. The goal is to scale up the system in a Commercialization Readiness Pilot to bring faster, cheaper results to clinical settings. If successful, patients with suspected bloodstream infections could receive timely, life-saving therapy and better outcomes. The study will involve clinical testing to refine workflow and ensure reliable performance in real-world labs.
Why it matters
Potential benefit: Faster and more accurate detection of bloodstream yeast infections could lead to earlier treatment and improved survival.
How similar studies have gone: Previous SBIR work demonstrated high sensitivity and specificity, supporting potential clinical impact.
Where this research is happening
-
Scanogen, INC.
Baltimore, United States Active
Researchers
- Principal investigator: Celedon, Alfredo Andres — Scanogen, INC.
- Study coordinator: Celedon, Alfredo Andres
Related research
Other NIH-funded projects on the same topics.
-
Bloodstream yeast infection test directly from blood
A new automated test kit can detect most yeasts causing bloodstream infections directly from a patient’s blood to help doctors start the right antifungal treatment sooner.
-
Fast blood test to find bacteria and tell which antibiotics will work
A new blood test that finds bacteria and shows which antibiotics will work for people with suspected bloodstream infections.
-
Faster diagnosis for yeast bloodstream infections
This work is creating a quick test to find yeast infections in the blood, helping doctors treat patients faster.
-
Rapid blood test to detect many bloodstream infections
A fast blood test that finds many different germs directly from whole blood for people with suspected bloodstream infections or sepsis.
-
Rapid diagnosis of bacterial sepsis without culture
This study is testing a new, fast way to find bacteria in blood samples from patients with sepsis, so doctors can start the right treatment in just one hour instead of waiting days, making it easier for everyone involved.
-
Quick identification and testing of blood infections using whole blood samples
This study is working on a fast test that can quickly find infections in your blood and check which antibiotics will work best, helping doctors treat you more effectively and sooner.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.