NIH-funded research R01 grant

Quick identification and testing of blood infections using whole blood samples

Official title: Rapid ID and AST Directly from Whole Blood Using Single Molecule Detection

Funded at Scanogen, INC. · NIH-11040347 · Data updated 2026-11-12

This study is working on a fast test that can quickly find infections in your blood and check which antibiotics will work best, helping doctors treat you more effectively and sooner.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionScanogen, INC.
NIH-funded
Lab location1 site (Baltimore, UNITED STATES)
Project startJanuary 30, 2023
Project endDecember 31, 2027
Funding year2025
Award (this year)$785,440
NIH project number5R01AI175063-03
Project IDNIH-11040347 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients experiencing bloodstream infections, particularly those at risk of antibiotic-resistant infections.

Less likely to help

Patients who do not have bloodstream infections or those whose infections are not caused by bacteria may not benefit from this research.

What this research studies

This research aims to develop a rapid diagnostic platform that can identify bloodstream infections and test for antibiotic susceptibility directly from whole blood samples. By utilizing a novel technique called Single MOlecule Tethering (SMOLT), the platform is designed to provide results within hours instead of days, allowing for timely and targeted treatment. The approach focuses on detecting bacteria and determining their resistance to antibiotics quickly, which is crucial for effective patient care. If successful, this method could significantly improve the management of infections caused by resistant organisms.

Why it matters

Potential benefit: If successful, this research could lead to faster and more effective treatment options for patients with bloodstream infections.

How similar studies have gone: Other research has shown promise in rapid diagnostic techniques for infections, suggesting that this approach could be a significant advancement in the field.

Where this research is happening

  • Scanogen, INC.
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Celedon, Alfredo Andres — Scanogen, INC.
  • Study coordinator: Celedon, Alfredo Andres

Related research

Other NIH-funded projects on the same topics.

  • Bloodstream infection detection directly on whole blood

    A new automated test detects yeast infections in a patient’s blood quickly, helping doctors start the right antifungal treatment sooner.

    NIH research Scanogen, INC. · Baltimore, UNITED STATES · NIH-11416610

  • Bloodstream yeast infection test directly from blood

    A new automated test kit can detect most yeasts causing bloodstream infections directly from a patient’s blood to help doctors start the right antifungal treatment sooner.

    NIH research Scanogen, INC. · Baltimore, UNITED STATES · NIH-11352556

  • Fast blood test to find bacteria and tell which antibiotics will work

    A new blood test that finds bacteria and shows which antibiotics will work for people with suspected bloodstream infections.

    NIH research Scanogen, INC. · Baltimore, UNITED STATES · NIH-11249969

  • Faster diagnosis for yeast bloodstream infections

    This work is creating a quick test to find yeast infections in the blood, helping doctors treat patients faster.

    NIH research Scanogen, INC. · Baltimore, UNITED STATES · NIH-11140525

  • Rapid blood test to detect many bloodstream infections

    A fast blood test that finds many different germs directly from whole blood for people with suspected bloodstream infections or sepsis.

    NIH research Scanogen, INC. · Baltimore, UNITED STATES · NIH-11139424

  • Rapid diagnosis of bacterial sepsis without culture

    This study is testing a new, fast way to find bacteria in blood samples from patients with sepsis, so doctors can start the right treatment in just one hour instead of waiting days, making it easier for everyone involved.

    NIH research Scanogen, INC. · Baltimore, UNITED STATES · NIH-11090450

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.