Blood tests and simple cognitive tests to detect Alzheimer's early in clinics
Official title: Prospective validation and implementation of high-performing blood biomarkers and digital cognitive tests for detection of Alzheimer's disease in specialist memory clinic and primary care settings
Funded at Lunds Universitet · NIH-11374391 · Data updated 2026-11-12
A study will test new blood biomarkers and quick cognitive tests to detect Alzheimer’s disease more accurately in doctors’ offices and memory clinics.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lunds Universitet NIH-funded |
| Lab location | 1 site (Lund, Sweden) |
| Project start | September 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $471,388 |
| NIH project number | 5R01AG083740-04 |
| Project ID | NIH-11374391 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults evaluated for suspected Alzheimer’s disease in memory clinics or primary care settings who consent to biomarker testing and follow-up.
✕Less likely to help
Patients without Alzheimer's-related pathology or those not undergoing ongoing diagnostic workups may see limited or no benefit.
What this research studies
This project will prospectively validate high-performing blood biomarkers like phospho-tau217 and digital cognitive tests in real-world clinical settings. Researchers will enroll patients seen in memory clinics and primary care and compare biomarker results with standard clinical diagnoses to determine added diagnostic value. The study aims to identify which patients benefit most from these biomarkers and how they can guide treatment decisions in routine practice. The effort builds on existing biomarker protocols and seeks to support faster, more reliable diagnoses of Alzheimer’s disease in Sweden.
Why it matters
Potential benefit: If successful, patients could receive more accurate and timely diagnoses, leading to earlier and more appropriate care.
How similar studies have gone: Similar biomarker-based approaches have shown promise, but real-world validation in clinical practice is crucial and ongoing.
Where this research is happening
-
Lunds Universitet
Lund, Sweden Active
Researchers
- Principal investigator: Palmqvist, Sebastian — Lunds Universitet
- Study coordinator: Palmqvist, Sebastian
Related research
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Better primary care for older adults with Alzheimer's and related dementias
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.