NIH-funded research Sbir 2 grant

Blood fatty acids as a simple early warning for insulin resistance

Official title: Testing a blood fatty acid algorithm as an earlier and easier predictor of insulin resistance

Funded at Omegaquant Analytics, LLC · NIH-11406411 · Data updated 2026-11-12

A patient-friendly blood test using fatty acids to predict who might develop insulin resistance or type 2 diabetes, so people can take action sooner.

More Insulin Resistance research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionOmegaquant Analytics, LLC
NIH-funded
Lab location1 site (Sioux Falls, United States)
Project startMay 22, 2023
Project endJuly 31, 2028
Funding year2026
Award (this year)$1,038,181
NIH project number2R44DK136409-02A1
Project IDNIH-11406411 on NIH RePORTER

Who could benefit from this research

Could help

Adults who are at risk for prediabetes or type 2 diabetes, particularly those who have blood glucose in the prediabetes range or are concerned about insulin resistance.

Less likely to help

People without elevated risk markers or those who would not benefit from early biomarker-based risk prediction may not see a direct benefit.

What this research studies

This project aims to use a blood-fat profile to flag people at high risk for prediabetes and type 2 diabetes before high blood sugar appears. It leverages machine learning and clinical lab measurements to identify patterns that predict future hyperglycemia. The goal is to offer an accessible, inexpensive way to identify at-risk individuals and guide lifestyle or medical steps to prevent disease progression. The work is conducted by OmegaQuant Analytics, a clinical lab with expertise in fatty acid testing, in collaboration with a university-affiliated team. It builds on prior Phase I findings suggesting blood fatty acids can signal risk years ahead of traditional tests.

Why it matters

Potential benefit: If successful, this approach could enable earlier lifestyle changes and interventions to prevent or delay diabetes.

How similar studies have gone: Previous work and the Phase I project indicate potential in using fatty acid patterns to predict risk, with promising but still early results.

Where this research is happening

  • Omegaquant Analytics, LLC
    Sioux Falls, United States
    Active

Researchers

  • Principal investigator: Jackson, Kristina Harris — Omegaquant Analytics, LLC
  • Study coordinator: Jackson, Kristina Harris

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.