Biochemical map of how exercise changes the body
Official title: A biochemical roadmap of exercise signal
Funded at Broad Institute, INC. · NIH-11534401 · Data updated 2026-11-12
Scientists are studying how exercise changes key molecules in the blood to better understand the body’s response to physical activity.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Broad Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | December 14, 2016 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $198,001 |
| NIH project number | 3U24DK112340-08S2 |
| Project ID | NIH-11534401 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults who participate in exercise programs and provide blood samples for analysis.
✕Less likely to help
People not involved in exercise studies or who do not provide blood samples may not directly benefit.
What this research studies
This project uses advanced labs to measure many blood substances before and after exercise to see how our bodies respond at the biochemical level. Researchers will analyze thousands of plasma samples from adults who completed different exercise routines to map timing and type-specific changes. The results could help tailor exercise programs to improve health and prevent disease.
Why it matters
Potential benefit: If successful, the work could lead to personalized exercise strategies based on blood markers.
How similar studies have gone: Prior large-scale analyses have shown consistent links between exercise and metabolic changes in blood, supporting further mapping in this framework.
Where this research is happening
-
Broad Institute, INC.
Cambridge, United States Active
Researchers
- Principal investigator: Gerszten, Robert E — Broad Institute, INC.
- Study coordinator: Gerszten, Robert E
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.