Atherosclerosis Core for analyzing artery lesions and immune cells
Official title: Atherosclerosis core
Funded at New York University D/b/a NYU Long Island School of Medicine · NIH-11327661 · Data updated 2026-11-12
A central NYU Langone/LONG ISLAND check-in provides expert tissue analysis and gene data to researchers studying how arteries harden and why immune cells contribute to the disease.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University D/b/a NYU Long Island School of Medicine NIH-funded |
| Lab location | 1 site (Mineola, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $209,124 |
| NIH project number | 5P01HL160470-04 |
| Project ID | NIH-11327661 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are patients whose tissue samples or data are included in the program projects studying atherosclerosis and macrophage biology through the core.
✕Less likely to help
Patients not contributing tissue samples or data to the core or not connected to ASCVD research would not directly benefit.
What this research studies
This grant funds a shared core that helps other projects study atherosclerotic plaques, macrophages, and gene expression in myeloid cells. It offers services like tissue staining, immunohistochemistry, laser capture microdissection, and preparation of samples for RNA sequencing. By standardizing methods and centralizing data analysis, it aims to accelerate understanding of how plaques form and how immune cells influence them. Researchers can access the core to get high-quality, reproducible molecular and cellular data without maintaining their own specialized equipment.
Why it matters
Potential benefit: If successful, patients with ASCVD could benefit from faster translational insights leading to better prevention or treatment strategies.
How similar studies have gone: Previous vascular biology cores have improved efficiency and data quality, but this specific integrated core is tailored to atherosclerosis and myeloid biology with modern sequencing.
Where this research is happening
-
New York University D/b/a NYU Long Island School of Medicine
Mineola, United States Active
Researchers
- Principal investigator: Fisher, Edward a — New York University D/b/a NYU Long Island School of Medicine
- Study coordinator: Fisher, Edward a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.