Analyzing metabolic networks to understand health outcomes
Network Models for Metabolomics
['FUNDING_R01'] · UNIVERSITY OF MASSACHUSETTS AMHERST · NIH-10656396
This study is looking at how the chemical processes in our bodies can differ between groups of people and how those differences might affect health, like the risk of having a stroke, to help find better ways to treat individuals based on their unique metabolic profiles.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MASSACHUSETTS AMHERST (nih funded) |
| Locations | 1 site (HADLEY, UNITED STATES) |
| Trial ID | NIH-10656396 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced network-based methods to analyze data from metabolomics studies, which examine the chemical processes within the body. It aims to identify how different metabolic networks vary among groups and how these variations relate to health outcomes, such as the risk of stroke. By using a Bayesian approach, the study will incorporate both existing biological pathways and data-driven correlations to enhance the understanding of metabolic interactions. The findings could lead to identifying specific metabolites that influence health conditions, providing insights into personalized treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for cardiovascular diseases or those with metabolic disorders.
Not a fit: Patients with unrelated health conditions or those not at risk for metabolic or cardiovascular issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cardiovascular diseases and other health conditions through targeted metabolic interventions.
How similar studies have performed: Previous research using network-based approaches in metabolomics has shown promise in identifying metabolic pathways related to various health outcomes, suggesting potential for success in this study.
Where this research is happening
HADLEY, UNITED STATES
- UNIVERSITY OF MASSACHUSETTS AMHERST — HADLEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BALASUBRAMANIAN, RAJI — UNIVERSITY OF MASSACHUSETTS AMHERST
- Study coordinator: BALASUBRAMANIAN, RAJI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cardiovascular Diseases, cardiovascular disorder, Coronary heart disease, Coronary Disease, atherosclerotic heart disease