Analyzing how individual cells behave and develop in tissues
In vivio single-cell analysis of dynamic cell behaviors
This study is looking at how individual cells move and change over time in tissues using special imaging techniques, which could help us better understand how our bodies develop and how diseases work.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11041051 on NIH RePORTER |
What this research studies
This research focuses on using advanced imaging techniques to observe and track the behavior of individual cells within tissues over time. By employing fluorescence 3D time-lapse imaging, researchers can monitor cell movements and lineage differentiation in real-time, providing insights into how tissues form and develop. The study aims to develop deep learning tools for accurate cell tracking and to integrate various imaging modalities to enhance our understanding of cell dynamics. This innovative approach could lead to breakthroughs in understanding complex biological processes and diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to tissue development or abnormalities, such as birth defects.
Not a fit: Patients with stable, non-progressive conditions or those not related to tissue development may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of tissue development and potentially inform new treatments for developmental disorders and diseases.
How similar studies have performed: Previous research has shown success in using imaging and deep learning techniques to analyze cell behavior, indicating that this approach has potential for significant advancements.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Bao, Zhirong — Sloan-Kettering Inst Can Research
- Study coordinator: Bao, Zhirong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.