AI-powered total parenteral nutrition for premature newborns
Official title: An AI-driven total parenteral nutrition platform for cost-effective and scientifically personalized nutrition for premature newborns
Funded at Takeoff41, INC. · NIH-11412694 · Data updated 2026-11-12
A new AI-driven system aims to guide and personalize total parenteral nutrition for premature babies in NICUs to improve growth and health outcomes while reducing costs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Takeoff41, INC. NIH-funded |
| Lab location | 1 site (Portola Valley, United States) |
| Project start | September 13, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $903,784 |
| NIH project number | 5R42HD115517-03 |
| Project ID | NIH-11412694 on NIH RePORTER |
Who could benefit from this research
✓Could help
Premature or other newborns in NICUs who require TPN nutrition.
✕Less likely to help
Newborns not needing TPN or in settings without NICU access may not benefit.
What this research studies
This project will create an AI-based TPN platform (TPN2.0) using a decade of data to link nutrient mixtures with infant health outcomes. It will first define standardized, manufacturable TPN units that can still be personalized for each baby, then test the platform in real clinical settings to show it performs as well as or better than current practices. The work builds on prior models that predict adverse outcomes from maternal and child health records and will be validated in real NICU environments. By making TPN safer, more affordable, and easier to administer, this project could reduce errors and improve long-term health for preterm infants.
Why it matters
Potential benefit: If successful, the platform could lower costs, reduce TPN-related errors, and improve growth and health outcomes for premature newborns.
How similar studies have gone: Preliminary AI-based health prediction models have shown promise; this project extends that approach to nutrition in the NICU.
Where this research is happening
-
Takeoff41, INC.
Portola Valley, United States Active
Researchers
- Principal investigator: Phongpreecha, Thanaphong — Takeoff41, INC.
- Study coordinator: Phongpreecha, Thanaphong
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.