AI-powered tool to predict 2-year risk of late AMD
Official title: A Model for Predicting 2-Year Risk of Incident Late Age-related Macular Degeneration
Funded at Ihealthscreen, INC. · NIH-11552709 · Data updated 2026-11-12
A new AI software helps people at risk of age-related macular degeneration understand their 2-year risk and what steps could protect their vision.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ihealthscreen, INC. NIH-funded |
| Lab location | 1 site (Richmond Hill, UNITED STATES) |
| Project start | September 30, 2021 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $100,000 |
| NIH project number | 3R44EY031202-06S1 |
| Project ID | NIH-11552709 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults at risk for dry or wet AMD who may benefit from early screening and risk prediction.
✕Less likely to help
Patients without AMD risk factors or those not using ophthalmology screening may see minimal benefit.
What this research studies
This project aims to validate an AI-based software called iPredict-AMD that screens for and predicts late AMD. It builds on earlier AREDS findings and plans prospective trials and human factors studies to ensure it works well in real clinical settings. If successful, the tool could guide early interventions to prevent vision loss in people at risk. The effort includes compatibility with clinical workflows and plans for FDA consideration and commercialization.
Why it matters
Potential benefit: If successful, patients at risk for AMD could receive earlier, personalized risk information to guide eye care and preventive steps.
How similar studies have gone: Similar AI-based risk prediction efforts have shown promise, but prospective validation is still needed.
Where this research is happening
-
Ihealthscreen, INC.
Richmond Hill, United States Active
Researchers
- Principal investigator: Bhuiyan, Alauddin — Ihealthscreen, INC.
- Study coordinator: Bhuiyan, Alauddin
Related research
Other NIH-funded projects on the same topics.
-
Active cycling program to support vision and daily living in Veterans with AMD
A 6-month online group spin cycling program is tested to help Veterans with age-related macular degeneration maintain vision and improve daily functioning.
-
Transplanting stem-cell–derived retinal cells to treat dry AMD
A medical team is testing a stem cell therapy to replace damaged retinal cells in adults with dry age-related macular degeneration.
-
RPESC-derived RPE Transplant for Dry AMD in adults
A new cell-based therapy derived from RPESCs is being tested to help adults with dry age-related macular degeneration regain vision.
-
New high-resolution OCT biomarkers to map early AMD changes
A new imaging approach using advanced OCT methods will help doctors see early changes in age-related macular degeneration to guide treatment and improve quality of life for older adults.
-
Targeting inflammation in age-related macular degeneration
Aims to understand how inflammation drives age-related macular degeneration in people and explore new targets to slow or stop vision loss.
-
Early atrophic AMD: understanding how the disease progresses to protect vision
This NIH grant studies how age-related macular degeneration advances in its early atrophic stage to help prevent vision loss.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.