NIH-funded research R01 grant

Adolescent outcomes after very preterm birth using a holistic exposome approach

Official title: Adolescent Outcomes in Infants Born Very Preterm: An Exposome Approach

Funded at Women and Infants Hospital-Rhode Island · NIH-11446657 · Data updated 2026-11-12

This grant aims to understand how a wide range of environmental, biological, and social factors together influence development in kids born very preterm.

More Preterm research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWomen and Infants Hospital-Rhode Island
NIH-funded
Lab location1 site (Providence, United States)
Project startSeptember 21, 2026
Project endJune 30, 2031
Funding year2026
Award (this year)$936,631
NIH project number1R01HD120477-01A1
Project IDNIH-11446657 on NIH RePORTER

Who could benefit from this research

Could help

Children born very preterm (<32 weeks gestation) and their families who can be followed over time.

Less likely to help

Some children may not show strong associations with the studied exposures or may not benefit from the tailored insights in the near term.

What this research studies

Babies born very preterm face higher risks for neurodevelopmental and behavioral challenges as they grow. The study will look at multiple exposures and personal factors across time to see how they combine to shape outcomes from infancy through adolescence. Researchers will use holistic data methods to capture the total exposome and its relationship to development in these children. Findings could help tailor interventions to those most at risk.

Why it matters

Potential benefit: If successful, the work could lead to better prediction of which preterm children need extra support and inform targeted prevention strategies.

How similar studies have gone: Prior research supports the value of holistic exposure models; this project aims to extend those approaches to very preterm populations.

Where this research is happening

  • Women and Infants Hospital-Rhode Island
    Providence, United States
    Active

Researchers

  • Principal investigator: Lester, Barry M. — Women and Infants Hospital-Rhode Island
  • Study coordinator: Lester, Barry M.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.