A wireless system to improve bladder function after spinal cord injury
Official title: Wireless, Closed?loop System to Restore Urological Dysfunction after Spinal Cord Injury
Funded at University of Houston · NIH-11120286 · Data updated 2026-11-12
This study is testing a new, wireless device that uses smart technology to help people with spinal cord injuries manage their bladder better, making it easier to empty the bladder and reduce issues like infections.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | May 5, 2025 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $206,132 |
| NIH project number | 1R21EB037317-01 |
| Project ID | NIH-11120286 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced severe spinal cord injuries leading to bladder detrusor sphincter dyssynergia.
✕Less likely to help
Patients with mild spinal cord injuries or those without bladder dysfunction may not benefit from this research.
What this research studies
This research aims to develop a wireless, battery-free implant that uses artificial intelligence to manage bladder function in individuals with spinal cord injuries. The device will monitor bladder activity and provide electrical stimulation to improve bladder emptying, addressing complications like urinary tract infections and renal failure. By utilizing soft, stretchable electrodes, the system will facilitate a more natural voiding process. The effectiveness of this approach will be tested in a rat model of spinal cord injury.
Why it matters
Potential benefit: If successful, this research could significantly enhance the quality of life for patients with spinal cord injuries by improving bladder control and reducing complications.
How similar studies have gone: While the approach of using AI for neuromodulation is innovative, similar bioelectronic devices have shown promise in other areas of neuromodulation, indicating potential for success.
Where this research is happening
-
University of Houston
Houston, United States Active
Researchers
- Principal investigator: Li, Zhengwei — University of Houston
- Study coordinator: Li, Zhengwei
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.