A wireless system to improve bladder function after spinal cord injury
Wireless, Closed?loop System to Restore Urological Dysfunction after Spinal Cord Injury
This study is testing a new, wireless device that uses smart technology to help people with spinal cord injuries manage their bladder better, making it easier to empty the bladder and reduce issues like infections.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11120286 on NIH RePORTER |
What this research studies
This research aims to develop a wireless, battery-free implant that uses artificial intelligence to manage bladder function in individuals with spinal cord injuries. The device will monitor bladder activity and provide electrical stimulation to improve bladder emptying, addressing complications like urinary tract infections and renal failure. By utilizing soft, stretchable electrodes, the system will facilitate a more natural voiding process. The effectiveness of this approach will be tested in a rat model of spinal cord injury.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced severe spinal cord injuries leading to bladder detrusor sphincter dyssynergia.
Not a fit: Patients with mild spinal cord injuries or those without bladder dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance the quality of life for patients with spinal cord injuries by improving bladder control and reducing complications.
How similar studies have performed: While the approach of using AI for neuromodulation is innovative, similar bioelectronic devices have shown promise in other areas of neuromodulation, indicating potential for success.
Where this research is happening
Houston, United States
- University of Houston — Houston, United States (Active)
Researchers
- Principal investigator: Li, Zhengwei — University of Houston
- Study coordinator: Li, Zhengwei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.