NIH-funded research NIH-funded research

A social norms program to help urban adolescent girls and young women use PrEP

Official title: A Pilot Social Norms Intervention to Engage Social Networks of Urban Adolescent Girls and Young Women in PrEP: Msichana Salama

Funded at American University · NIH-11538496 · Data updated 2026-11-12

A small pilot in Africa will test whether shaping social norms within networks of out-of-school AGYW can help increase PrEP use and adherence to reduce HIV risk.

More PrEP research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionAmerican University
NIH-funded
Lab location1 site (Washington, UNITED STATES)
Project startSeptember 17, 2026
Project endAugust 31, 2029
Funding year2026
Award (this year)$106,067
NIH project number3R34MH138249-01A1S1
Project IDNIH-11538496 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are out-of-school adolescent girls and young women aged 15–24 who are at risk for HIV in Dar es Salaam.

Less likely to help

Girls who are not at risk for HIV or who are not interested in PrEP may not benefit.

What this research studies

This project tests a social norms intervention called Msichana Salama with networks of mostly out-of-school adolescent girls and young women in Dar es Salaam, Tanzania. It is a 24-network pilot trial aiming to see if changing peer norms can support PrEP initiation and ongoing use, alongside safer behaviors. The study will measure feasibility, PrEP uptake, adherence, and HIV-risk practices over time to inform a larger effort.

Why it matters

Potential benefit: If successful, the intervention could make PrEP more acceptable and easier to use among high-risk AGYW, potentially lowering new HIV infections.

How similar studies have gone: Prior work has shown that social network approaches can influence health behaviors, but this exact PrEP-focused, network-based pilot is exploratory.

Where this research is happening

  • American University
    Washington, United States
    Active

Researchers

  • Principal investigator: Yamanis, Thespina Jeanne — American University
  • Study coordinator: Yamanis, Thespina Jeanne

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.