NIH-funded research NIH-funded research

A Social Norms Pilot to Boost PrEP Use Among Out-of-School Adolescent Girls and Young Women in Africa

Official title: A Pilot Social Norms Intervention to Engage Social Networks of Urban Adolescent Girls and Young Women in PrEP: Msichana Salama

Funded at American University · NIH-11191098 · Data updated 2026-11-12

A small pilot project tests a social-network approach to help out-of-school adolescent girls and young women in Africa start and stay on PrEP to prevent HIV.

More PrEP research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionAmerican University
NIH-funded
Lab location1 site (Washington, UNITED STATES)
Project startSeptember 10, 2026
Project endAugust 31, 2029
Funding year2026
Award (this year)$145,735
NIH project number1R34MH138249-01A1
Project IDNIH-11191098 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are out-of-school adolescent girls and young women aged 15–24 who are at risk for HIV and live in Dar es Salaam, Tanzania.

Less likely to help

Participants not at risk for HIV or not willing to engage with PrEP and social-network activities may not benefit.

What this research studies

This project will test a social norms-based program called Msichana Salama to encourage PrEP use and adherence among networks of mostly out-of-school AGYW in Dar es Salaam. It will engage 24 sociocentric networks (about 224 participants) to see if changing how peers influence risk behaviors can increase PrEP uptake and ongoing use. The study uses a practical, community-based approach to measure feasibility, adherence, and reductions in risky behaviors like transactional sex. Results will inform larger efforts to scale PrEP delivery through social networks that support young women’s health.

Why it matters

Potential benefit: If successful, the intervention could increase PrEP uptake and adherence among AGYW, potentially lowering HIV infection risk in this high-need group.

How similar studies have gone: Previous work showed feasibility of network-based approaches; this pilot aims to establish feasibility and acceptability in a new setting and population.

Where this research is happening

  • American University
    Washington, United States
    Active

Researchers

  • Principal investigator: Yamanis, Thespina Jeanne — American University
  • Study coordinator: Yamanis, Thespina Jeanne

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.