NIH-funded research NIH-funded research

A program to prevent youth from vaping nicotine

Official title: Pilot and Feasibility Testing of a Peer-led Program to Prevent Youth Nicotine Vaping: The YES-CAN! Program

Funded at University of Colorado Denver · NIH-10930149 · Data updated 2026-11-12

This study is testing a fun school program called YES-CAN! that helps middle and high school students work together to create videos and messages to prevent vaping, aiming to change how their friends think about it and encourage healthier choices.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startSeptember 15, 2023
Project endJuly 31, 2026
Funding year2024
Award (this year)$234,000
NIH project number5R34DA058218-02
Project IDNIH-10930149 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents aged 12 to 18 who are at risk of or currently engaging in nicotine vaping.

Less likely to help

Patients who are not adolescents or those who do not engage in or are not at risk for nicotine vaping may not benefit from this research.

What this research studies

This research investigates a school-based program called YES-CAN! aimed at preventing nicotine vaping among adolescents. The program utilizes peer-led strategies, where students collaborate with adults to create health messages and videos that resonate with their peers. By focusing on youth engagement and positive health behaviors, the initiative seeks to change attitudes and norms around vaping in middle and high school communities. The program will be implemented in two school communities, where students will participate in a credit-earning class and produce videos to promote refusal skills and positive coping mechanisms.

Why it matters

Potential benefit: If successful, this research could significantly reduce nicotine vaping among adolescents, leading to improved health outcomes.

How similar studies have gone: Previous research has shown that peer-led interventions can be effective in changing health behaviors among adolescents, suggesting potential success for this approach.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Crane, Lori a. — University of Colorado Denver
  • Study coordinator: Crane, Lori a.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.