A new therapeutic approach to help adults quit smoking

Who could benefit from this research

What this research studies

This grant focuses on developing a new therapy to help people 21 and older quit nicotine addiction from cigarettes and e-cigarettes. It describes moving a potential treatment from early development toward something that could be tested in people. The work is conducted by Flik Therapeutics in Philadelphia and involves a translational plan to bring a promising therapy closer to patients who want to quit nicotine. The project outlines how the therapy will be tested for safety and effectiveness as part of a structured development timeline.

Why it matters

Where this research is happening

• Flik Therapeutics, INC.
  Philadelphia, United States Active

Researchers

• Principal investigator: Heiden, Brendan — Flik Therapeutics, INC.
• Study coordinator: Heiden, Brendan

Related research

Other NIH-funded projects on the same topics.

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  A new program combines motivational interviewing and mindfulness-based therapy to help people on methadone treatment quit tobacco and other drugs at the same time.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11382249

• Mindfulness and motivational coaching to help people on methadone quit smoking and reduce other drug use

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  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11364696

• A mentoring program to improve tobacco dependence research.

  This study is creating a mentoring program to help new researchers learn how to improve treatments for people trying to quit smoking, making sure they work well for different individuals based on their unique needs.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11080886

• Helping people in methadone treatment quit smoking and other drugs

  This study is looking for people in methadone treatment for opioid use who also smoke, to try out a new 8-week group program that teaches mindfulness and emotional skills to help them feel better and reduce their chances of relapsing into substance use.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-10589481

• Volitional Help Sheets to Support Smoking Cessation in Clinical Care

  This pilot tests whether adding a short, personalized if-then planning tool helps people in a French clinic quit smoking when used alongside usual care.

  Recruiting Clinique de la Mitterie · Lille · NCT07910214

• Extended tobacco support for people experiencing homelessness

  This program tests whether extending tobacco treatment to 6 months with pharmacist counseling, monthly nicotine replacement deliveries, and phone wellness coaching helps adults experiencing homelessness quit smoking compared with a 3-month package.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07148232

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.