NIH-funded research R01 grant

Helping people in methadone treatment quit smoking and other drugs

Official title: Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement for Tobacco Dependence and Other Drug use in Methadone Treatment

Funded at Rutgers Biomedical and Health Sciences · NIH-10589481 · Data updated 2026-11-12

This study is looking for people in methadone treatment for opioid use who also smoke, to try out a new 8-week group program that teaches mindfulness and emotional skills to help them feel better and reduce their chances of relapsing into substance use.

More Mindfulness research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers Biomedical and Health Sciences
NIH-funded
Lab location1 site (Newark, UNITED STATES)
Project startSeptember 30, 2022
Project endSeptember 29, 2025
Funding year2022
Award (this year)$2,300,742
NIH project number1R01DA057631-01
Project IDNIH-10589481 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals receiving methadone treatment for opioid use disorder who also smoke cigarettes or use other substances.

Less likely to help

Patients who are not currently undergoing methadone treatment or do not have a dual diagnosis of opioid and tobacco use may not benefit from this research.

What this research studies

This research focuses on individuals undergoing methadone treatment for opioid use disorder, particularly those who also smoke tobacco. It aims to implement a novel behavioral intervention called Mindfulness-Oriented Recovery Enhancement (MORE), which combines mindfulness training and emotional regulation techniques over an 8-week group therapy program. The goal is to address the intertwined issues of tobacco and substance use by improving motivation and self-efficacy, ultimately reducing relapse rates. Participants will engage in activities designed to enhance their emotional well-being and reward processing, which are often disrupted in those with substance use disorders.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment strategies for individuals struggling with both opioid and tobacco dependence, improving their chances of recovery.

How similar studies have gone: Previous research has shown promise for mindfulness-based interventions in substance use treatment, but this specific approach targeting polysubstance use in methadone patients is novel.

Where this research is happening

  • Rutgers Biomedical and Health Sciences
    Newark, United States
    Active

Researchers

  • Principal investigator: Cooperman, Nina — Rutgers Biomedical and Health Sciences
  • Study coordinator: Cooperman, Nina

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.